Psoriasis, a chronic autoimmune condition, causes inflammation that leads to skin changes. The same underlying triggers that drive psoriasis may also pose problems for your heart. Psoriasis increases inflammation throughout the body, including the cardiovascular system. Chronic inflammation has long been associated with an increased risk of heart attack and stroke.
The Link Between Psoriasis and Heart Disease
There is strong evidence linking severe psoriasis with heart disease, but the exact relationship between the two conditions is still unclear.
Genetic Risk
Psoriasis shares some common factors with heart disease, including genetic relationships.
Inflammatory Pathways
Both conditions may share inflammatory pathways that drive the progression of heart disease and cause psoriasis plaques. The inflammation that makes the skin red and flaky is similar to the inflammation that causes blockages in the arteries.
Pro-inflammatory Proteins
People with psoriasis have elevated levels of pro-inflammatory proteins, which may contribute to the development of heart disease.
Insulin Resistance
Insulin resistance can lead to type 2 diabetes, which increases the risk of heart disease.
Cholesterol Buildup
Psoriasis is linked with abnormal cholesterol and triglycerides, which are types of lipoproteins that can lead to cholesterol buildup.
Risk Factors and Life Expectancy
People with psoriasis have about a 50 percent higher risk of heart attack and stroke, independent of traditional risk factors. Patients with psoriasis are less likely to have these risk factors identified and adequately treated. People with psoriasis that is severe enough to require pills, phototherapy, or biologics have a five-year reduction in life expectancy, mostly due to excess risk of cardiovascular disease.
Treatment
Some medications typically prescribed for moderate to severe psoriasis may improve cardiovascular health. Medications that may lower the risk of heart attack and stroke include Methotrexate, TNF inhibitors, such as adalimumab (Humira), and Ustekinumab (Stelara).
Reducing Your Risk
To manage psoriasis symptoms and protect your heart health, take your medications as prescribed. Effective treatment of psoriasis can help manage skin symptoms and keep inflammation under control.
Healthy Diet
Diet can’t cure or prevent psoriasis, but it can reduce psoriasis symptoms and the risk of comorbidities, including heart disease. Maintain a healthy weight, exercise regularly, limit fried and highly processed foods, focus on eating whole grains and plenty of fruits and vegetables, and limit alcohol.
Quit Smoking
Quitting smoking can significantly improve both psoriasis and heart health.
Open Dialogue with Your Care Team
Regular checkups are critical for monitoring your heart health.
Conclusion
The link between psoriasis and heart disease highlights the importance of managing psoriasis effectively and adopting a heart-healthy lifestyle. Individuals with psoriasis should be aware of the increased risk of cardiovascular issues and take proactive steps to reduce that risk. By focusing on lifestyle changes and effective psoriasis treatment, people can mitigate the risks associated with psoriasis and heart disease, ultimately improving their overall health and quality of life. Regular communication with healthcare providers is essential for monitoring and managing both conditions effectively.
